Niacin (Table 1) Biological rationale Niacin is the precursor of pyrimidine nucleotides nicotinamide adenine dinucleotide (NAD), including NAD + and the reduced form NADH, and nicotinamide adenine dinucleotide phosphate (NADP), including NADP + and the reduced form NADPH
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The methylation process is responsible for: Cellular Repair : synthesis of nucleic acids, production & repair of DNA & mRNA Detoxification and Neurotransmistter Production : interconversion of amino acids Healthy Immune System Function : formation & maturation of red blood cells, white blood cells & platelet production The 677T variant is most commonly associated with early heart disease and stroke and the 1298C variant with a variety chronic illnesses, but either anomaly can cause a wide variety of health problems
Cunha, P
