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Inhibition of the differentiation of human myeloid cell lines by redox changes induced through glutathione depletion

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When these complexes are damaged by lipid peroxidation (the oxidative degradation of lipids in the mitochondrial membrane), ATP production grinds to a halt

Previous studies have shown that in diabetic patients, the pancreas, especially islet cells, is often characterized by excessive iron accumulation, and the level of antioxidant enzymes in cells is low, which makes these cells susceptible to oxidative stress [244, 245]

doi: 10.3390/ijms161226138 271 LloydSMArnoldJSreekumarA

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