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Both Novo Nordisk and Lilly are responding to competition from compounding pharmacies, which have been able to offer discounted versions of semaglutide and tirzepatide under FDA regulations applying to medicines deemed to be in short supply
The dramatic horror stories typically involve doses well beyond what research protocols suggest
However, their high price tags $12,648 per year for tirzepatide and $13,618 per year for semaglutide exceed the typical cost-effectiveness threshold of $100,000 to $150,000 per quality-adjusted life-year (QALY)
Applying a gentle, fragrance-free moisturizer can help reduce dryness and peeling
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