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References Stockler-Ipsiroglu S, van Karnebeek CD

If you are over 65 and have experienced any of the following, metformin might not be safe for you: Coma Diabetic ketoacidosis (blood sugar so high that it required emergency treatment) Liver disease Stroke Tell your healthcare provider if you are pregnant or plan to become pregnant before taking metformin

PMID 11016951

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