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Engelmann quotes historian James Timberlake as saying, "[E]conomic developments were conspiring to give the economic argument for temperance a boost." With the growth of mass production at the turn of the century, a new ethos of scientific and industrial efficiency birthed a cultural argument against inebriation.) [] The city of Temperance in Monroe County is so named for its creation by a series of deed restrictions or "temperance clauses" on land sold by temperance advocates Lewis and Marietta Anstead

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Further large-scale studies are warranted to clarify creatines role in gastrointestinal health