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Weakened ligaments can lead to: Joint deformity Contractures (a permanent tightening that causes the joint to shorten and stiffen) Increased pain Rheumatoid arthritis can also cause damage to blood vessels, skin, lungs, eyes, heart, and the nervous system

Potential Mechanisms

Chin J Integr Med

Its dramatic age-related decline is significant: plasma concentrations average 200 ng/mL at age 20 but typically plummet to 80 ng/mL by age 60a 60% reduction correlating with visible aging and reduced healing capacity

The few vitamin E studies that included a placebo treatment group revealed that vitamin E did not appear to produce better results than the placebo, raising the question of whether vitamin E is an effective treatment

M., & Wathoni, N