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Taken as a once-weekly injection, tirzepatide is often chosen by women who want a stronger effect on appetite, or who have plateaued on another GLP-1
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However, native GLP-1 undergoes rapid enzymatic degradation by dipeptidyl peptidase-4 (DPP-4), resulting in a short half-life (~ 2 min), thus limiting its clinical applicability [65, 66]
Beta-alanine helps buffer lactic acid build-up, reducing muscle fatigue, while creatine supports ATP regeneration for sustained power output