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Prior to starting the study, the investigators used PASS software (version 11) to calculate minimum sample size 11

Ultrastructural changes in enterocytes in subjects with Hashimotos thyroiditis

Quan et al., 2021)

After induction, rats were treated with 7-Hydroxyflavone at various doses (5, 10 and 15 mg/kg) and metformin (300 mg/kg) for 14 consecutive days

BPC-157 acts primarily at the local injury site, stimulating fibroblast proliferation, angiogenesis, and collagen synthesis

In wound-healing models, GHK-Cu has been shown to increase expression and activation of MMP-2 specifically, alongside stimulating new collagen and glycosaminoglycan production