Dixon's group demonstrated that the GSH exporter MRP1 sensitizes HPA1 erastin-treated cells to ferroptosis and concordantly, MRP1 inhibition leads to a retention of GSH and leads to ferroptosis resistance (58)
DSIP has been studied for various potential physiological roles, including: Stress response and adaptation Pain modulation Immune system regulation Antioxidant properties Effects on endocrine function DSIP has been investigated for potential applications in sleep disorders, pain management, and substance withdrawal syndromes
That is the focus of this live episode of Scale Up Your Practice, recorded at the Canadian Obesity Summit 2026 in Montreal
That matters in chronic conditions, where treatment can last for months or even years
Borges G, Bagge CL, Cherpitel CJ, et al
J.BambinoK.SharmaA.KitajewskiJ.et al (2010)