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The key secondary endpoints demonstrated significant reductions in atherogenic lipid levels and liver stiffness over 52 weeks in the 80 mg and 100 mg resmetirom

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Convert vial amount to micrograms (if needed): mg 1,000 = mcg Concentration: total amount (mcg) total liquid (mL) = mcg/mL Draw volume: target amount (mcg) concentration (mcg/mL) = mL U100 units: mL 100 = syringe units Worked example (math only) If a vial is labelled 5 mg (5,000 mcg) and you add 2 mL, the concentration is 2,500 mcg/mL

Because it contains topiramate, an anti-seizure drug, theres a chance it can have a rebound effect and set off a seizure if someone taking one of the two top doses stops it suddenly, Folek says