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The rats were anesthetized with intraperitoneal injection of pentobarbital sodium (50 mg/kg), and dorsal hair was shaved and depilated with hair removal cream

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IL-1 is a typical inflammatory mediator produced by nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing 3 (NLRP3) inflammasome, leading to myocardial hypertrophy, heart failure, and coronary atherosclerosis [85, 86]

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[10] Pregnancy & Breastfeeding Pyridoxine (vitamin B) is generally considered safe for use during pregnancy when administered at recommended doses

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