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Skin appears more luminous, tone looks more uniform, and texture may feel smoother

High glucose promotes O-GlcNAcylation of ACSL4 to induce ferroptosis of renal tubular epithelial cell

XG: Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writingoriginal draft, Writingreview and editing

The tissues were dewaxed and rehydrated through a series of xylene and ethanol changes

h , Uptake of [ 3 H]GSH after incubation with 400 M unlabelled GSH and 4 M [ 3 H]GSH into ER at indicated times

Event: 1634: Increase, Oxidative damage to DNA Short Name: Increase, Oxidative DNA damage Key Event Component AOPs Including This Key Event Stressors Biological Context Cell term Organ term Evidence for Perturbation by Stressor Overview for Molecular Initiating Event H 2 O 2 and KBrO 3 A concentration-dependent increase in oxidative lesions was observed in both Fpg- and hOGG1-modified comet assays of TK6 cells treated with increasing concentrations of glucose oxidase (an enzyme that generates H 2 O 2 ) and potassium bromate for 4 hours (Platel et al., 2011)