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GPNA can inhibit ASCT2 and other glutamine transporters, such as sodium-coupled neutral amino acid transporter 1 (SNAT1), SNAT2, large neutral amino acid transporter 1 (LAT1), and LAT2, leading to decreased uptake of essential amino acids (Freidman et al., 2022)

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This route allows for optimal bioavailability and effective delivery of the drug, particularly in managing conditions like diabetes and obesity

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