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It was shown in vitro using ZF cell lines that constant ACTH treatment led to larger increase in pCREB and steroidogenic gene transcription at the start of treatment but the cells became unresponsive to the stimuli over time (158)

As shown in Supplementary Figure 1, we did not observe a significant difference in the cell number between the control and ABT263 treatment group

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None of them are uncommon

CJC 1295 consists of 29 amino acids and is utilized to enhance GH production in a controlled and sustained manner