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References Thapar, A., Cooper, M

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In an eight-week placebo-controlled study of 60 women with BMIs from 25 to 28, those taking 176.5 mg per day of Satiereala type of saffron extractshowed greater reductions in snacking frequency and body weight compared to the placebo group

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1 Introduction 1.1 Atherosclerosis and coronary artery disease Coronary artery disease (CAD) is a cardiovascular condition occuring due to atherosclerotic plaque accumulation in the epicardial arteries, whether obstructive or non-obstructive ( Inflammation plays a key role in the formation of atherosclerotic plaquesthe primary pathological mechanism underlying CAD ( (IFN- ) and tumour necrosis factor (TNF)- , produced by immune cells, endothelial cells, platelets and fibroblasts are associated with atherosclerosis onset and progression

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