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How GLP-1 receptor agonists might help in DFUs: Improve microvascular function and tissue perfusion Reduce inflammation and oxidative stress in wound beds Modulate apoptosis (cell death) and promote tissue repair Relieve neuropathic pain through neuroprotective effects Support weight loss, reducing pressure and metabolic burden on the foot Interestingly, GLP-1 receptor agonists have shown positive dermatologic outcomes in conditions such as hidradenitis suppurativa and androgenetic alopecia, hinting at their regenerative potential

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