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Together, these peptides work on complementary pathways to enhance growth hormone release in a physiological, pulsatile manner without directly supplying synthetic hormones

We refer to the species formed after NADPH binding (the ES downstream species) as NADP + -TGR(H) reduced complexes, indicating that electrons are inside the polypeptide chain of the enzyme giving rise to the EH 2 and the EH 4 species (Fig