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Differential Diagnosis Hyperpigmented macules or patches that might be confused with CALMs include pigmentary mosaicism (segmental pigmentation disorder, linear nevoid hyperpigmentation), early nevus spilus (before the speckles have appeared), Becker melanosis (without obvious hypertrichosis), mastocytoma, mosaic (segmental) neurofibromatosis, and postinflammatory hyperpigmentation

LV is funded by a Sir Henry Dale Fellowship awarded jointly by the Wellcome Trust and the Royal Society (#221805/Z/20/Z), and also acknowledges the support of the Slovak Grant Agencies VEGA (#2/0004/23) and APVV (#21-0299)

Androgens play a role in the development of secondary sexual characteristics in men (17)

Human fibrocytes coexpress thyroglobulin and thyrotropin receptor

The mechanism of action is unclear possibly by preventing tau protein aggregation or increasing amyloid- clearance by enhancing proteasome activities [19,20]

Today, we are paying close attention as strong evidence shows these medications lower the risk of heart attack, stroke, and death from heart disease even in people without diabetes