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Li R, et al
IGF-1 DES is a truncated version (des(1-3)IGF-1) that has higher potency at the receptor (~5-10x) but a very short half-life (~2030 minutes)
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Stellpflug SJ , Gardner RL , Leroy JM , Ellsworth H , Zwank MD
Both dexmedetomidine and propofol are associated with similar secondary hemodynamic effects.110,111 Dexmedetomidine has been well tolerated in patients with chronic liver disease, without increasing side effects, albeit patients require more time before extubation, once the medication is suspended.112 Opioids are frequently employed in combination with a benzodiazepine for moderate sedation
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