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Overall, mast cells have 50 200 granules in the cytoplasm of the cell, storing histamine, heparin, tryptase, cytokines, etc.[ref] The image below shows mast cell (stained purple) degranulation under a microscope.[ref] Allergies: Activating mast cells by Type 1 hypersensitivity In addition to reacting to antigens on pathogens, such as bacteria, the IgE can also be primed to link with antigens on proteins that are not pathogens, referred to as allergens
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Pharm Res 26:914925 Zhu H, Gao J, Wang L et al (2018) Invitro study on reversal of ovarian cancer cell resistance to cisplatin by naringin via the nuclear factor-B signaling pathway
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