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110,111 Whilst duration of NAC supplementation appears to be important, another potential cause for some of the heterogeneity observed in clinical trials may be the length of time patients have been suffering from schizophrenia, with those with a history of schizophrenia for 20 years or more responding best to NAC

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11), suggesting that RRTE and its lipid-lowering components may modulate cellular steatosis via the PI3K-Akt and PPAR signaling pathways in vitro

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