If fatigue is persistent after the adaptation period, check whether total caloric intake has dropped below approximately 1,200 to 1,400 calories per day (the minimum for most people to maintain energy and lean mass)
Summary Semaglutide is a synthetic analogue of the naturally occurring glucagon-like peptide-1 (GLP-1), which plays a critical role in regulating glucose metabolism, appetite, and energy balance1,2
If you are taking medications that affect clotting, check with your prescriber about how to proceed, because personal medical context changes the risk calculus
Early on, the focus is on medication consistency and side effect patterns
Other Weight Loss Medications Mounjaro is usually prescribed on its own for weight loss
PlexusDx offers the Precision Peptide Genetic Test ($99 add-on or $298 standalone) to help provide context on peptide pathway predispositionsa complementary assessment that can support conversations with any prescriber, including those using telehealth platforms
