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Circosta C, Pasquale RD, Palumbo DR, Samperi S, Occhiuto F

What the research firmly supports: BPC-157's gut healing, vascular, and neuroprotective mechanisms (strong preclinical evidence) Thymosin Alpha-1's immune modulating and T-cell restorative effects (strong preclinical + clinical evidence in viral disease) TB-500's cardiovascular repair and angiogenic properties (strong preclinical, early human data) What the research does not yet confirm: Randomised controlled trial data specifically in long COVID populations Optimal dosing, sequencing, and duration specifically for PASC Long-term safety data for extended post-viral use This doesn't mean these peptides don't work for long COVID

Qualified medical guidance should be sought before any consideration of use

Most infusions last between 1.5 and 3 hours, depending on your dose and how your body responds

Most researchers report that fatigue resolves within 2-3 weeks of reaching a stable dose

Research Applications Compared Because the mechanisms differ, the two compounds have accumulated their strongest evidence in somewhat different areas with meaningful overlap in wound healing and angiogenesis