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After CMS finalized the rule on April 4, Eli Lilly and Novo Nordiskthe makers of Zepbound and Ozempicsaw their stocks drop 6.5% and 6.8%, respectively, by market close, according to Zacks Investment Research

They may adjust your dosing schedule to better suit your needs or even suggest an alternative weight loss medication

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Content Updated: March 13, 2026 Key takeaways Microdosing with semaglutide involves administering smaller doses than the standard amount

Antacids: Can sometimes help by neutralizing stomach acid and reducing indigestion