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Yes, vitamin B12 can trigger acne in some people, although it does not affect everyone

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Chromatogram: The visual output of an HPLC test showing the purity peaks

Although it was careful not to claim apples-to-apples comparisons due to methodological and other differences, the paper cited benchmarks that seemed to indicate better-than-average results

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Variants of the IFN-induced helicase C domain 1 (IFIH1) gene are related to protection vs vitiligo by inhibiting IFN- production