Upon cleavage, the scaffold is partially released from the capsid to make room for the viral genome while the capsid acquires an icosahedral shape, producing so-called C-capsids
Part of the results were presented in the conference (Nutrition 2020 Live Online, American Society for Nutrition, Settle, USA)
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Heart failure is a common complication of obesity [61, 62], and clinical trials have shown that GLP-1 analogs, particularly tirzepatide, can improve cardiac function and reduce the risk of heart failure in people with obesity [63]