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Development of renal disease in people at high cardiovascular risk: Results of the HOPE randomized study

This medication carries a boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

Its ability to promote weight loss is also a major benefit, as excess weight is a key driver of insulin resistance

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Mol Metab 2021;46:101102

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