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The April 2026 FDA action removes them from the Category 2 restricted compounding list effective April 23, 2026, and the FDAs Pharmacy Compounding Advisory Committee will review their compounding eligibility under 503A at its July 23-24, 2026 meeting

Until that process completes, do not treat the advisory review as approval

One cause is dermatographism, a condition where light scratching or pressure creates raised lines

It is not a drug, food, or cosmetic , and must not be misused, misbranded, or represented as such

10.2741/heizmann

The cartilage finding is notable because it suggests the peptide acts through pathways relevant to connective tissue repair, not only lipolysis