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It has been found that gold nanoparticles can interact with fungal mitochondria, leading to inappropriate reduction of molecular oxygen during adenosine triphosphate (ATP) synthesis through coupled proton and electron transfer reactions and destruction of mitochondrial membrane [94]

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doi: 10.1016/j.immuni.2018.04.022 29 ZengHUmarSRustBLazarovaDBordonaroM

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The inclusion of NAC makes it ideal for those whose glutathione levels may be depleting rapidly