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16 Recent developments add momentum to the notion that larger degrees of weight loss (1020% of body weight) may result in meaningful reductions in cardiovascular outcomes

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They are a prognostic sign in several atherothrombotic diseases, including acute coronary syndrome, thrombosis, and stroke

This phenomenon is central to its study in models of tissue aging and repair

Tirzepatide, a dual GLP-1/GIP receptor agonist, has demonstrated cardiovascular benefits in clinical trials, yet some patients report heart rate changes during the first weeks of treatment

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