Patients who gained weight while prescribed any of the GLP-1 medications studied had no statistically significant change in their TSH levels
This prolonged transit time ensures that patients feel satiated for longer periods, minimizes cravings, and ultimately establishes the sustainable caloric deficit required for effective and long-term weight reduction
For instance, an interaction that increases the risk of bleeding or enhances the effect of blood sugar-lowering medications could pose serious health risks
The researchers suggest that changes in gut microbiome composition, particularly involving Akkermansia muciniphila and Parabacteroides distasonis , may explain the effects on GLP-1 and other gut-brain signaling molecules
GLP-1 and GLP-1 agonist medications: Increase insulin production, reduce appetite, and slow down digestion so you feel full longer, eat less, and lose weight
2019;68(suppl 1):985-P