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Destruction of alveolar walls in emphysematous regions leads to a reduction in the alveolar capillary bed, which diminishes lung elastic recoilforming the core pathological basis for expiratory dyspnea in affected patients ( 4.2.1 Core cell types and their roles Macrophages are key effector cells in emphysema development, degrading elastic fibers of alveolar walls by secreting MMP-9 and MMP-12
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doi: 10.1016/j.mrgentox.2008.11.012
Lancet Psychiat
In studies, researchers linked low levels of vitamin D to symptom flares, fatigue, poor mental function, kidney disease, osteoporosis and a greater risk of heart disease and high blood pressure (x, x, x, x, x)
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