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Endocrinology 1999;140:24450

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[70] But this drug (Avonex) produced flu-like symptoms in up to 61 percent of patients who took it at the currently recommended lower dose, as well as nausea in 33 percent and anemia in eight percent

If any of these markers are missing, discuss with your provider or pharmacy about potential formulation issues

Natural flavones like quercetin and apigenin act as TrkB agonists, directly binding to the receptors extracellular domain to activate the downstream CREB pathway, thereby reducing apoptosis, oxidative stress, and protein aggregation in cellular models of neurodegeneration (Chiu et al., 2023)

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