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Alzheimers Disease from the Amyloidogenic Theory to the Puzzling Crossroads between Vascular, Metabolic and Energetic Maladaptive Plasticity

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18 Smoking, biofuel smoke-induced oxidative stress and excessive protease production are major factors in COPD pathogenesis that cause alveolar cell death, destruction of the extracellular matrix in the alveolar region and loss of alveolar structure