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The fix is switching the dose to before 10 AM

Epitalon mechanism is better understood at the enzymatic level (AANAT upregulation, pCREB activation) but the full picture of how it achieves tissue-specific pineal protection remains unclear

Dosage: In human sleep studies, researchers have used intravenous doses of 25nmol per kilogram.13 14 Intravenous administration boasts higher bioavailability than, say, the subcutaneous route,28 which is the more common mode of administration for peptides, so a home-use case would likely involve a higher dose

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