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Localized cryotherapy has shown benefits for targeted inflammation and pain relief (Hauser et al., 2014)

Chou YJ, Tai YH, Dai YX et al (2022) Obsessive-compulsive disorder and the associated risk of autoimmune skin: diseases a nationwide population-based cohort study

Outcome: After 5 months, BP decreased, hsCRP reduced, and oxidative stress biomarkers improved

But 30mg in 1mL gives you 30mg/mL, three times your previous concentration

Hawkins et al., 2013

community sources report joint-related protocols Lung health -- mouse models demonstrated protection against fibrosis and emphysema, driving community interest Anti-aging / longevity -- the gene-expression data showing modulation of 4,000+ genes has generated significant community interest in systemic anti-aging protocols Common audience: users pursuing systemic effects beyond what topical delivery can achieve, who accept the lower evidence threshold of animal data and community reports