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Understanding your genetic predisposition helps your provider optimize both your dose and schedule for maximum efficacy and minimal side effects

Its tough to say, so we definitely need more hard science to look at that in a more objective way, Spittler said

TH potentiates the production of non-12-OH FXR-antagonistic BAs Recent evidence suggests that a couple of non-12-OH BAs, including T(/)MCA, (T/G)UDCA, and (T)HDCA, can exert FXR-antagonistic effects 4,9,10,29 , while intestinal FXR inhibition is able to stimulate GLP-1 production and secretion in L cell 11

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