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The Leave-one-out method was used for sensitivity analysis, each SNP was eliminated in turn, and the remaining SNPs were used as IVs for two sample MR analysis to determine the degree to which the causal association effect was affected by a single SNP
2006b;35(1):628
The imbalance between Th17 cells and Treg cells was found to be a crucial factor in the pathogenesis of UC [60,61,62]
Last updated: March 22, 2026 Introduction to Inflammatory Bowel Disease The etiology of Inflammatory bowel disease (ulcerative colitis and Crohns disease) is complex, with genetic predisposition, an altered microbiome, environmental factors and a weakened epithelial (gut) barrier function triggering a chronic immune response in the mucosal layer
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