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Other meta-analyses, however, despite showing that patients with BD present lower peripheral levels of tryptophan, Kyn or KYNA, did not find any significant differences between manic and depressed phases [230]

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Metabolic disorders affect how your body processes nutrients and enzymes

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identifying high-risk individuals who could adopt preventative diets) or as indicators of therapeutic response (seeing the microbiome shift towards a healthy state might precede and predict clinical improvement)