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Clinical Points Weight gain and increased risk of hyperglycemia have been associated with the use of antidepressant medications

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From hours 6 to 9, subjects underwent a hyperinsulinemic-euglycemic clamp initiated with a prime dose of 160 mU/m 2 /min insulin for 5 minutes and then 80 mU/m 2 /min for 5 minutes, followed by a constant infusion of 40 mU/m 2 /min from the hours 6 to 9, with glycemia maintained at the fasted level using a variable infusion of 20% dextrose