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Individuals who are sensitive to hormonal changes might be more susceptible to this effect
To our knowledge, no studies have examined the effects of SGLT-2Is on total kidney volume (TKV) in patients with diabetes and only one study has examined the effect of GLP-1RAs [29]
A phase 3 trial of BPDO-1603 (NCT04229927) was started in February 2020 and is estimated to be completed in March 2023
where reflux-type symptoms occurred, they may have been captured under broader dyspepsia or GI discomfort categories
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