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The exclusion criteria included review articles, duplicate articles, patents, abstracts, conference papers, and studies with no in vivo investigations

168 WuYRanLYangYGaoXPengMLiuSet al

Cell Signal 23:15461554

CONCLUSIONS A unifying view, provided by integrative physiology and sometimes called a holistic approach, is especially important for understanding how the brain acts, regulates all functions of the living body and at the same time is regulated by body signals [95]

values for ELISA assay samples were measured using a Benchmark Plus plate-reading spectrophotometer under the control of Microplate Manager software (Bio-Rad Laboratories, Hercules, CA)

Adverse Effects of Obesity Obesity is not just a matter of carrying excess weight

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