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10.1038/s41387-022-00214-2 [DOI] [PMC free article] [PubMed] [Google Scholar] McClean P., Hlscher C

[3] Persulfides are intermediates in the biosynthesis of iron-sulfur proteins [4] and are invoked as precursors to hydrogen sulfide, a biological signaling molecule

However, at excessive levels, ROS exert toxic effects and directly oxidize biological macromolecules, such as proteins, nucleic acids and lipids, further exacerbating the development of inflammatory responses and causing various inflammatory diseases

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