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These findings suggest that targeting accessible receptors in the CVOs of the brain could be a promising therapeutic strategy for the treatment of obesity

doi: 10.1007/s00401-014-1328-5

When your blood sugar rises, specialized cells in your pancreas release insulin, a hormone Insulin tells your bodys cells to soak up glucose Your cells then either store glucose (as glycogen) for later use or metabolize it and use it for immediate energy Issues can occur when your body becomes insulin resistant, meaning you have a decreased response to insulin compared with someone with normal insulin sensitivity

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ARA-290 selectively activates the innate repair receptor, a signaling complex that shifts your immune response from inflammation toward tissue repair