10.1016/0092-8674(93)80066-N Cell 67 HoggN.SinghR
Dilutions WB: 1:500-1:2,000, ICC/IF: 1:50-1:200 Reactivity Human, Mouse, Rat Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 373-474 of human Glutathione Synthetase (Glutathione Synthetase (GSS)) (NP_000169.1)
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This thiol-containing molecule is an important antioxidant in cell compartments with high concentrations in cytosol (111 mM), nuclei (315 mM), and mitochondria (511 mM)
Meldonium has been described as metabolized via 3-hydroxypropionic acid with formation of succinic acid ( Effects on oxidative stress and inflammation-linked mitochondrial dysfunction Hypoxia and intense exertion can promote inflammatory signaling and oxidative stress, contributing to mitochondrial dysfunction
Discontinuing application may result in a gradual return to baseline hair density.