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Mol Metab (2016) 5:62634

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The results convincingly demonstrate that protein aggregation induces senescence of many cell types in the brain, and that senolytics effectively reduce pathogenesis (3537)

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"We really don't know those answers." But Reichert said she's excited about where the field seems headed: the possibility of better access to medications , such as a pill, lower prices as well as behavioural programs from insurance companies coupled with efforts to reduce the shame and bias people with bigger bodies face to support healthy lifestyle changes

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Importantly, an intact C-terminal end of albumin is required for optimal binding to FcRn, and we recently demonstrated that truncation of the last leucine residue at position 585 (L585) reduced the binding affinity by 5-fold 60

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