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This makes sure the patient gets the right amount, which is key for treatment success

Routes of administration include intraventricular, intracarotid, intravenous and intraperitoneal injection each producing different effective central exposures of an unstable peptide

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This causes high oxidative stress, mitochondrial dysfunction, and cell death of the hepatocytes.[ref] As these cells die, inflammatory cascades perpetuate the oxidative stress, leading to bleeding, fibrosis, or possibly liver failure

10.1038/bjc.2011.510 46 GuineyS

Activation of mouse and human peroxisome proliferator-activated receptors (PPARs) by phthalate monoesters