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58,59 Overall, the future research direction of GLP-1RAs involves making them more similar to those in the human body, extending their duration of action, and creating oral formulations for easier administration

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Based on these initial studies and comprehensive characterization, liraglutide was selected as having the best properties, combining high receptor potency with pharmacokinetics (PK) that are optimum for OD dosing (43)

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72-75 "Palmitoylation of [delta]-catenin by DHHC5 mediates activity-induced synapse plasticity"