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Additionally, insulin resistance, chronic inflammation, and the psychological burden of managing chronic disease can all contribute to cognitive symptoms

Neither should be seen as a stand-alone fix the best outcomes come when these treatments are combined with lifestyle changes such as nutrition improvements, increased physical activity, and long-term behaviour support

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The half-life of approximately six days means doubling produces plasma levels significantly higher than intended, increasing side effect risk without proportional benefit

A small number of representative cases go to trial first