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In the meantime, the activated inflammatory factors trigger the production of substantial quantities of pro-fibrotic cytokines, which exacerbate oxidative stress in pulmonary tissue and intensify fibrosis (Obayashi et al., 2000

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It was reported that after 30 minutes of treatment, MOTS-c can exert its effects by entering the cells and exerting its effects

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Several natural compounds demonstrate DPP-4 inhibitory activity, though far weaker than pharmaceutical inhibitors

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